Thursday, 29 September 2016

Dibelet




Dibelet may be available in the countries listed below.


Ingredient matches for Dibelet



Glibenclamide

Glibenclamide is reported as an ingredient of Dibelet in the following countries:


  • Singapore

International Drug Name Search

Magnesium Pidolate




Scheme

Prop.INN

ATC (Anatomical Therapeutic Chemical Classification)

A12CC08

CAS registry number (Chemical Abstracts Service)

0062003-27-4

Chemical Formula

C10-H12-Mg-N2-O6

Molecular Weight

280

Therapeutic Category

Mineral supplement

Chemical Name

Magnesium, bis(5-oxo-L-prolinato-N1,O2)-, (T-4)-

Foreign Names

  • Magnesii pidolas (Latin)
  • Pidolsäure, Magnesiumsalz (German)

Generic Names

  • Magnesium Pidolate (OS: BANM)
  • Magnesium 5-oxopyrrolidine-2-carboxylate (IS)
  • Magnesium pyroglutamate (IS)
  • Magnesii pidolas (PH: Ph. Eur. 6)
  • Magnesium Pidolate (PH: BP 2010, Ph. Eur. 6)

Brand Names

  • Actimag
    Iquinosa, Spain


  • Biomag
    Baliarda, Argentina


  • Mag 2
    Cooper, Burkina Faso; Cooper, Benin; Cooper, Central African Republic; Cooper, Congo; Cooper, Cote D'ivoire; Cooper, Cameroon; Cooper, France; Cooper, Gabon; Cooper, Guinea; Cooper, Luxembourg; Cooper, Madagascar; Cooper, Mali; Cooper, Mauritania; Cooper, Mauritius; Cooper, Niger; Cooper, Senegal; Cooper, Chad; Cooper, Togo; Cooper, Zaire; Cooperation Pharmaceutique Française, Tunisia; Galenica, Greece; Sanofi-Aventis, Switzerland; Sanofi-Aventis, Italy


  • Magnolve
    Vitoria, Portugal


  • Mg 2 Plus
    Opalia, Tunisia


  • Solumag
    Boehringer Ingelheim International, Luxembourg; Geymonat, Italy; Uni-Pharma, Greece


  • Top Mag
    Medipha, Tunisia


  • Top-Mag
    Aérocid, France

International Drug Name Search

Glossary

BANMBritish Approved Name (Modified)
ISInofficial Synonym
OSOfficial Synonym
PHPharmacopoeia Name
Prop.INNProposed International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

Comenter




Comenter may be available in the countries listed below.


Ingredient matches for Comenter



Mirtazapine

Mirtazapine is reported as an ingredient of Comenter in the following countries:


  • Argentina

  • Mexico

  • Venezuela

Selegiline

Selegiline hydrochloride (a derivative of Selegiline) is reported as an ingredient of Comenter in the following countries:


  • Ecuador

International Drug Name Search

Wednesday, 28 September 2016

Amitraz




In some countries, this medicine may only be approved for veterinary use.

Scheme

Prop.INN

CAS registry number (Chemical Abstracts Service)

0033089-61-1

Chemical Formula

C19-H23-N3

Molecular Weight

293

Therapeutic Category

Insecticide

Chemical Names

N-Methyl-N'-2,4-xylyl-N-(N-2,4-xylylformimidoyl)formamidine (WHO)

N²-(2,4-Dimethylphenyl)-N¹-[(2,4-dimethylphenylimino)methyl]-N¹-methylformimidamid (IUPAC)

Foreign Names

  • Amitrazum (Latin)
  • Amitraz (German)
  • Amitraz (French)
  • Amitraz (Spanish)

Generic Names

  • Amitraz (OS: BAN, USAN)
  • BTS 27419 (IS)
  • U 36059 (IS: Upjohn)
  • Amitraz (PH: BP vet. 2007, USP 32)

Brand Names

  • Aludex (veterinary use)
    Intervet, United Kingdom; Intervet, Ireland


  • Amidip (veterinary use)
    Virbac, South Africa


  • Amigard (veterinary use)
    Pfizer Animal Health, South Africa


  • Amipor (Amitraz and Cypermethrin, + Piperonyl Butoxide (veterinary use))
    Virbac, South Africa


  • Amitik (veterinary use)
    Coopers Animal Health, Australia


  • Amitix (veterinary use)
    Schering-Plough Animal Health, South Africa


  • Amitraz (veterinary use)
    Bayer Australia Ltd Animal Health, Australia; Virbac, Germany


  • Apitraz (veterinary use)
    Biowet Pulawy, Poland


  • Apivar (veterinary use)
    Veto-Pharma, France


  • Apiwarol (veterinary use)
    Biowet Pulawy, Poland


  • Biocani Tique (veterinary use)
    Véto-Centre, France


  • Biowar (veterinary use)
    Biowet Pulawy, Poland


  • Ceva Amitraz (veterinary use)
    Ceva Animal Health, South Africa


  • Crede Ecto Imatraz (veterinary use)
    Experto Vet, South Africa


  • Crede Ecto Tracypor (Amitraz and Cypermethrin (veterinary use))
    Experto Vet, South Africa


  • Delete (Amitraz and Deltamethrin, + Piperonyl Butoxide (veterinary use))
    Intervet, South Africa


  • Deltaderm Demadex (veterinary use)
    Delvet, Australia


  • Demotick (veterinary use)
    Intervet, Italy


  • Ectodex (veterinary use)
    Alfamed, Portugal; Intervet, Germany; Intervet, France; Intervet, Netherlands; Intervet, South Africa


  • MDB Cypertraz (Amitraz and Cypermethrin (veterinary use))
    Ceva Animal Health, South Africa


  • Milbitraz (veterinary use)
    Bayer Animal Health, South Africa


  • Mitaban (veterinary use)
    Pharmacia & Upjohn vet, United States


  • Pertanol (veterinary use)
    Sociedade Permutadora, S.A., Portugal


  • Preventic (veterinary use)
    Virbac, Australia; Virbac, Switzerland; Virbac, Italy; Virbac, Luxembourg; Virbac, South Africa; Virbac de Portugal, Portugal


  • Préventic (veterinary use)
    Virbac, France


  • Promeris Duo (Amitraz and Metaflumizone (veterinary use))
    CEVA Vetpharma, Sweden; Fort Dodge Animal Health, South Africa; Fort Dodge Santé Animale, France; Scanvet, Finland


  • Supatraz (veterinary use)
    Cipla Agrimed, South Africa


  • Sytraz (veterinary use)
    Iapsa Portuguesa Pecuária, Lda, Portugal


  • Taktic (veterinary use)
    Intervet, Austria; Intervet, Belgium; Intervet, France; Intervet, United Kingdom; Intervet, Ireland; Intervet, Italy; Intervet, Netherlands; Intervet, South Africa; Intervet / Schering-Plough Animal Health, New Zealand; Intervet Schering-Plough Animal Health, Portugal; Intervet/Schering-Plough Animal Health, Australia; Veterinaria, Switzerland; Virbac, Australia


  • Tickamit (veterinary use)
    Quifipor - Química Fina Portuguesa, Lda., Portugal


  • Topline (veterinary use)
    Hoechst Roussel Vet, Portugal; Hoechst Vet, Ireland; Intervet, United Kingdom


  • Triatix (Amitraz and Deltamethrin, + Piperonyl Butoxide (veterinary use))
    Afrivet, South Africa


  • Triatix (veterinary use)
    Afrivet, South Africa

International Drug Name Search

Glossary

BANBritish Approved Name
IUPACInternational Union of Pure and Applied Chemistry
ISInofficial Synonym
OSOfficial Synonym
PHPharmacopoeia Name
Prop.INNProposed International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.

Inteban SP




Inteban SP may be available in the countries listed below.


Ingredient matches for Inteban SP



Indometacin

Indometacin is reported as an ingredient of Inteban SP in the following countries:


  • Japan

International Drug Name Search

Rubramin PC




Generic Name: cyanocobalamin

Dosage Form: injection, USP

Rubramin PC Description


Rubramin PC (Cyanocobalamin Injection) contains cyanocobalamin (vitamin B12) in a clear, red, sterile, nonpyrogenic, aqueous solution in a potency of 1000 mcg/mL (cobalt: 40 mcg/mL) for intramuscular use. Each mL of solution also contains 10 mg benzyl alcohol as a preservative and sodium chloride for isotonicity; pH has been adjusted between 4.5 and 7.0 with sodium hydroxide or hydrochloric acid.


Cyanocobalamin is very hygroscopic in the anhydrous form, and sparingly soluble in water (1:80). The vitamin B12 coenzymes are very unstable in light.


Cyanocobalamin may be chemically designated as 5,6-dimethyl-benzimidazolyl cyanocobamide. The structural formula is represented below:




Rubramin PC - Clinical Pharmacology


Vitamin B12 is essential to growth, cell reproduction, hematopoiesis, and nucleoprotein and myelin synthesis.


Cyanocobalamin is quantitatively and rapidly absorbed from intramuscular sites of injection; the plasma level of the compound reaches its peak within one hour after intramuscular injection. Absorbed vitamin B12 is transported via specific B12 binding proteins, transcobalamin I and II to the various tissues. The liver is the main organ for vitamin B12 storage.


Within 48 hours after injection of 1000 mcg of vitamin B12, 50 to 98 percent of the injected dose may appear in the urine. The major portion is excreted within the first eight hours.


Gastrointestinal absorption of vitamin B12 depends on the presence of sufficient intrinsic factor and calcium ions. Intrinsic factor deficiency causes pernicious anemia, which may be associated with subacute combined degeneration of the spinal cord. Prompt parenteral administration of vitamin B12 prevents progression of neurologic damage.


The average diet supplies about 5 to 15 mcg/day of vitamin B12 in a protein-bound form that is available for absorption after normal digestion. Vitamin B12 is not present in foods of plant origin, but is abundant in foods of animal origin. In people with normal absorption, deficiencies have been reported only in strict vegetarians who consume no products of animal origin (including milk products or eggs).


Vitamin B12 is bound to intrinsic factor during transit through the stomach; separation occurs in the terminal ileum in the presence of calcium, and vitamin B12 enters the mucosal cell for absorption. It is then transported by the transcobalamin binding proteins. A small amount (approximately 1 percent of the total amount ingested) is absorbed by simple diffusion, but this mechanism is adequate only with very large doses. Oral absorption is considered too unreliable in patients with pernicious anemia or other conditions resulting in malabsorption of vitamin B12.


Cyanocobalamin is the most widely used form of vitamin B12, and has hematopoietic activity apparently identical to that of the anti-anemia factor in purified liver extract. Hydroxycobalamin is equally as effective as cyanocobalamin, and they share the cobalamin molecular structure.



Indications and Usage for Rubramin PC


Rubramin PC is indicated for use as the flushing dose in the Schilling (vitamin B12 absorption) Test for pernicious anemia.



Contraindications


This preparation is contraindicated in patients who are sensitive to cobalt and/or vitamin B12.



Warnings


Patients who have early Leber’s disease (hereditary optic nerve atrophy) have been found to suffer severe and swift optic atrophy when treated with vitamin B12.


Fatal hypokalemia may occur when severe megaloblastic anemia is treated intensively with vitamin B12, as a result of increased erythrocyte potassium requirements (see PRECAUTIONS, Laboratory Tests).


Anaphylactic shock and death have been reported after parenteral vitamin B12 administration. An intradermal test dose is recommended before cyanocobalamin is administered to patients suspected of being sensitive to this drug.


This product contains benzyl alcohol. Benzyl alcohol has been reported to be associated with a fatal "Gasping Syndrome" in premature infants.



Precautions



General


Doses of vitamin B12 exceeding 10 mcg daily may produce a hematologic response in patients who have a folate deficiency. Indiscriminate administration of vitamin B12 may mask the true diagnosis of pernicious anemia.


Vitamin B12 deficiency that is allowed to progress for longer than three months may produce permanent degenerative lesions of the spinal cord. Doses of folic acid greater than 0.1 mg per day may result in hematologic remission in patients with vitamin B12 deficiency. Neurologic manifestations will not be prevented with folic acid, and if not treated with vitamin B12, irreversible damage will result.



Laboratory Tests


Patients with pernicious anemia have about three times the incidence of carcinoma of the stomach as the general population, so appropriate tests for this condition should be carried out when indicated.



Drug Interactions


Neomycin, colchicine, para-aminosalicylic acid, or excessive alcohol intake longer than two weeks may cause malabsorption of vitamin B12. Chloramphenicol and other drugs having bone marrow suppressant properties may cause a lack of therapeutic response to vitamin B12; this effect may be due to interference with erythrocyte maturation.



Drug/Laboratory Test Interactions


Most antibiotics, methotrexate, and pyrimethamine invalidate folic acid and vitamin B12 diagnostic microbiological blood assays.



Carcinogenesis, Mutagenesis, Impairment of Fertility


Long-term studies in animals to evaluate carcinogenic potential have not been done. There is no evidence from long-term use in patients with pernicious anemia that cyanocobalamin is carcinogenic. Pernicious anemia is associated with an increased incidence of carcinoma of the stomach, but this is believed to be related to the underlying pathology and not to treatment with cyanocobalamin.



Pregnancy


Pregnancy Category C. Adequate and well-controlled studies have not been done in pregnant women. However, vitamin B12 is an essential vitamin and requirements are increased during pregnancy. Amounts of vitamin B12 that are recommended by the Food and Nutrition Board, National Academy of Science-National Research Council for pregnant women (4 mcg daily) should be consumed during pregnancy.



Nursing Mothers


Vitamin B12 is known to be excreted in human milk. Amounts of vitamin B12 that are recommended by the Food and Nutrition Board, National Academy of Science-National Research Council for lactating women (4 mcg daily) should be consumed during lactation.


Vitamin B12 appears in the milk of nursing mothers in concentrations that approximate the mother’s vitamin B12 blood level.



Pediatric Use


Safety and effectiveness in pediatric patients has not been established.



Adverse Reactions


No serious toxic reactions have been reported following the intramuscular administration of cyanocobalamin. The following allergic-type reactions have been reported rarely; the relationship of these reactions to cyanocobalamin or other components in the preparation is unknown.


Generalized—anaphylactic shock and death have been reported with administration of parenteral vitamin B12 (see WARNINGS)


Cardiovascular—pulmonary edema and congestive heart failure early in treatment, peripheral vascular thrombosis


Hematologic—polycythemia vera


Gastrointestinal—mild transient diarrhea


Dermatologic—itching, transitory exanthema, urticaria


Miscellaneous—feeling of swelling of entire body



Overdosage


No overdosage has been reported with this drug.



Rubramin PC Dosage and Administration


Rubramin PC (Cyanocobalamin Injection) should be visually inspected for particulate matter and color prior to administration; the solution is clear red.


Do not administer intravenously.



Schilling Test*


The flushing dose is 1000 mcg injected intramuscularly. For procedure see the insert packaged with Rubratope®-57 (Cyanocobalamin Co 57) capsules or diagnostic kit (see the DOSAGE AND ADMINISTRATION section).



How is Rubramin PC Supplied


Rubramin PC (Cyanocobalamin Injection USP)


Unimatic® Single Dose Syringes


The syringes are supplied with sterile disposable 22-gauge, 1-1/4-inch needles.


     1000 mcg (1 mL):     NDC 0270-0519-16



Storage


Protect from light (keep syringes in carton). Store at controlled room temperature; avoid freezing.



Directions for Use of

UNIMATIC® single dose syringe


1)

Screw the threaded tip of the plunger rod clockwise into the cartridge plunger and push forward a few millimeters to break any friction between the cartridge plunger and syringe barrel.


2)

Holding syringe erect, aseptically remove the rubber cap from the tip of the syringe and attach the sterile, disposable needle using a push-twist action.


3)

Remove the needle guard, hold the syringe erect, and push plunger forward until a drop appears at tip of needle and all of the air is evacuated. Following the usual aspiration procedure complete the injection.


4)

Destroy the needle and syringe immediately after use.


Manufactured for

Bracco Diagnostics Inc.

Princeton, N.J. 08543

by E.R. Squibb & Sons Inc.

New Brunswick, N.J. 08903


J3-662G

Printed in USA

May 1995








Rubramin PC 
cyanocobalamin  injection, solution










Product Information
Product TypeHUMAN PRESCRIPTION DRUGNDC Product Code (Source)0270-0519
Route of AdministrationINTRAMUSCULARDEA Schedule    




















INGREDIENTS
Name (Active Moiety)TypeStrength
cyanocobalamin (cyanocobalamin)Active1000 MICROGRAM  In 1 MILLILITER
benzyl alcoholInactive10 MILLIGRAM  In 1 MILLILITER
sodium chlorideInactive 
sodium hydroxideInactive 
hydrochloric acidInactive 


















Product Characteristics
Color    Score    
ShapeSize
FlavorImprint Code
Contains      










Packaging
#NDCPackage DescriptionMultilevel Packaging
10270-0519-161 mL (MILLILITER) In 1 SYRINGENone

Revised: 10/2006Bristol-Myers Squibb Company

More Rubramin PC resources


  • Rubramin PC Side Effects (in more detail)
  • Rubramin PC Use in Pregnancy & Breastfeeding
  • Rubramin PC Drug Interactions
  • Rubramin PC Support Group
  • 5 Reviews for Rubramin PC - Add your own review/rating


Compare Rubramin PC with other medications


  • B12 Nutritional Deficiency
  • Pernicious Anemia
  • Schilling Test
  • Vitamin B12 Deficiency

Sinopryl




Sinopryl may be available in the countries listed below.


Ingredient matches for Sinopryl



Lisinopril

Lisinopril is reported as an ingredient of Sinopryl in the following countries:


  • Romania

  • Turkey

International Drug Name Search

Sylvan




Sylvan may be available in the countries listed below.


Ingredient matches for Sylvan



Drospirenone

Drospirenone is reported as an ingredient of Sylvan in the following countries:


  • Luxembourg

Ethinylestradiol

Ethinylestradiol is reported as an ingredient of Sylvan in the following countries:


  • Luxembourg

International Drug Name Search

Otiborin




Otiborin may be available in the countries listed below.


Ingredient matches for Otiborin



Boric Acid

Boric Acid is reported as an ingredient of Otiborin in the following countries:


  • Finland

International Drug Name Search

Gen-Glybe




Gen-Glybe may be available in the countries listed below.


Ingredient matches for Gen-Glybe



Glibenclamide

Glibenclamide is reported as an ingredient of Gen-Glybe in the following countries:


  • Canada

International Drug Name Search

Alendronat Streuli




Alendronat Streuli may be available in the countries listed below.


Ingredient matches for Alendronat Streuli



Alendronic Acid

Alendronic Acid sodium trihydrate (a derivative of Alendronic Acid) is reported as an ingredient of Alendronat Streuli in the following countries:


  • Switzerland

International Drug Name Search

Tuesday, 27 September 2016

Imipénem Cilastatine Mylan




Imipénem Cilastatine Mylan may be available in the countries listed below.


Ingredient matches for Imipénem Cilastatine Mylan



Cilastatin

Cilastatin sodium salt (a derivative of Cilastatin) is reported as an ingredient of Imipénem Cilastatine Mylan in the following countries:


  • France

Imipenem

Imipenem monohydrate (a derivative of Imipenem) is reported as an ingredient of Imipénem Cilastatine Mylan in the following countries:


  • France

International Drug Name Search

Prohist




In the US, Prohist (chlophedianol/phenylephrine/triprolidine systemic) is a member of the drug class upper respiratory combinations and is used to treat Cough and Nasal Congestion.

US matches:

  • Prohist CD Liquid

  • Prohist CF Liquid

  • Prohist LQ Liquid

  • ProHist DM

Ingredient matches for Prohist



Promethazine

Promethazine hydrochloride (a derivative of Promethazine) is reported as an ingredient of Prohist in the following countries:


  • South Africa

International Drug Name Search

oxycodone and acetaminophen


a-seet-a-MIN-oh-fen, ox-i-KOE-done hye-droe-KLOR-ide


Oral route(Tablet)

Acetaminophen has been associated with cases of acute liver failure, at times resulting in liver transplant and death. Most of the cases of liver injury are associated with the use of acetaminophen at doses that exceed 4000 mg/day, and often involve more than one acetaminophen-containing product .



Commonly used brand name(s)

In the U.S.


  • Endocet

  • Magnacet

  • Narvox

  • Percocet

  • Perloxx

  • Primalev

  • Roxicet

  • Roxilox

  • Tylox

  • Xolox

Available Dosage Forms:


  • Tablet

  • Solution

  • Capsule

Therapeutic Class: Opioid/Acetaminophen Combination


Chemical Class: Oxycodone


Uses For oxycodone and acetaminophen


Oxycodone and acetaminophen combination is used to relieve moderate to moderately severe pain.


Acetaminophen is used to relieve pain and reduce fever in patients. It does not become habit-forming when taken for a long time. But acetaminophen may cause other unwanted effects when taken in large doses, including liver damage.


Oxycodone belongs to the group of medicines called narcotic analgesics (pain medicines). It acts on the central nervous system (CNS) to relieve pain.


When oxycodone is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely.


oxycodone and acetaminophen is available only with your doctor's prescription.


Before Using oxycodone and acetaminophen


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For oxycodone and acetaminophen, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to oxycodone and acetaminophen or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies have not been performed on the relationship of age to the effects of oxycodone and acetaminophen combination in the pediatric population. Safety and efficacy have not been established.


Geriatric


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of oxycodone and acetaminophen combination in the elderly. However, elderly patients are more likely to have age-related kidney or liver problems, which may require caution and an adjustment in the dose for patients receiving oxycodone and acetaminophen combination.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking oxycodone and acetaminophen, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using oxycodone and acetaminophen with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.


  • Naltrexone

Using oxycodone and acetaminophen with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Acetophenazine

  • Adinazolam

  • Alfentanil

  • Alprazolam

  • Amobarbital

  • Anileridine

  • Aprobarbital

  • Atazanavir

  • Brofaromine

  • Bromazepam

  • Brotizolam

  • Buprenorphine

  • Buspirone

  • Butabarbital

  • Butalbital

  • Butorphanol

  • Carisoprodol

  • Chloral Hydrate

  • Chlordiazepoxide

  • Chlorpromazine

  • Chlorzoxazone

  • Clarithromycin

  • Clobazam

  • Clonazepam

  • Clorazepate

  • Clorgyline

  • Codeine

  • Dantrolene

  • Desflurane

  • Dexmedetomidine

  • Dezocine

  • Diazepam

  • Diphenhydramine

  • Doxylamine

  • Enflurane

  • Erythromycin

  • Escitalopram

  • Estazolam

  • Eszopiclone

  • Ethchlorvynol

  • Ethopropazine

  • Fentanyl

  • Flumazenil

  • Flunitrazepam

  • Fluphenazine

  • Flurazepam

  • Fluvoxamine

  • Fospropofol

  • Furazolidone

  • Halazepam

  • Halothane

  • Hydrocodone

  • Hydromorphone

  • Hydroxyzine

  • Indinavir

  • Iproniazid

  • Isocarboxazid

  • Isoflurane

  • Itraconazole

  • Ketamine

  • Ketazolam

  • Ketoconazole

  • Lazabemide

  • Levorphanol

  • Linezolid

  • Lorazepam

  • Lormetazepam

  • Medazepam

  • Meperidine

  • Mephenesin

  • Mephobarbital

  • Meprobamate

  • Mesoridazine

  • Metaxalone

  • Methdilazine

  • Methocarbamol

  • Methohexital

  • Midazolam

  • Moclobemide

  • Morphine

  • Morphine Sulfate Liposome

  • Nalbuphine

  • Nefazodone

  • Nelfinavir

  • Nialamide

  • Nitrazepam

  • Nitrous Oxide

  • Nordazepam

  • Opium

  • Oxazepam

  • Oxycodone

  • Oxymorphone

  • Pargyline

  • Pentazocine

  • Pentobarbital

  • Perphenazine

  • Phenelzine

  • Phenobarbital

  • Prazepam

  • Procarbazine

  • Prochlorperazine

  • Promazine

  • Promethazine

  • Propiomazine

  • Propofol

  • Propoxyphene

  • Quazepam

  • Ramelteon

  • Rasagiline

  • Remifentanil

  • Ritonavir

  • Saquinavir

  • Secobarbital

  • Selegiline

  • Sertraline

  • Sevoflurane

  • Sodium Oxybate

  • Sufentanil

  • Tapentadol

  • Telithromycin

  • Temazepam

  • Thiethylperazine

  • Thiopental

  • Thioridazine

  • Toloxatone

  • Tranylcypromine

  • Triazolam

  • Trifluoperazine

  • Triflupromazine

  • Trimeprazine

  • Zaleplon

  • Zolpidem

Using oxycodone and acetaminophen with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Acenocoumarol

  • Carbamazepine

  • Isoniazid

  • Miconazole

  • Phenytoin

  • Rifampin

  • St John's Wort

  • Voriconazole

  • Warfarin

  • Zidovudine

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using oxycodone and acetaminophen with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use oxycodone and acetaminophen, or give you special instructions about the use of food, alcohol, or tobacco.


  • Ethanol

Using oxycodone and acetaminophen with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use oxycodone and acetaminophen, or give you special instructions about the use of food, alcohol, or tobacco.


  • Cabbage

Other Medical Problems


The presence of other medical problems may affect the use of oxycodone and acetaminophen. Make sure you tell your doctor if you have any other medical problems, especially:


  • Addison's disease (adrenal gland problem) or

  • Alcohol abuse, history of or

  • Brain tumor, history of or

  • Chronic obstructive pulmonary disease (COPD) or

  • CNS depression or

  • Cor pulmonale (serious heart condition) or

  • Drug dependence, especially with narcotics, or history of or

  • Enlarged prostate (BPH, prostatic hypertrophy) or

  • Head injuries, history of or

  • Hypothyroidism (an underactive thyroid) or

  • Hypovolemia (low blood volume) or

  • Kyphoscoliosis (curvature of the spine with breathing problems) or

  • Mental illness or

  • Problems with passing urine—Use with caution. May increase risk for more serious side effects.

  • Asthma, severe or

  • Hypercarbia (high carbon dioxide in the blood), severe or

  • Paralytic ileus (bowels stop working and may be blocked) or

  • Respiratory depression (very slow breathing)—Should not be used in patients with these conditions.

  • Hypotension (low blood pressure) or

  • Pancreatitis (inflammation of the pancreas) or

  • Seizures, history of or

  • Stomach problems—Use with caution. May make these conditions worse.

  • Kidney disease or

  • Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper Use of oxycodone and acetaminophen


Take oxycodone and acetaminophen only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. This is especially important for elderly patients, who may be more sensitive to the effects of pain medicines. If too much of oxycodone and acetaminophen is taken for a long time, it may become habit-forming and cause mental or physical dependence. Also, large amounts of acetaminophen may cause liver damage if taken for a long time.


Measure the oral liquid using the patient cup that comes with the package.


Carefully check the labels of all other medicines you are using, because they may also contain acetaminophen. It is not safe to use more than 4 grams (4,000 milligrams) of acetaminophen in one day (24 hours).


Dosing


The dose of oxycodone and acetaminophen will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of oxycodone and acetaminophen. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For moderate to moderately severe pain:
    • For oral dosage form (capsules):
      • Adults—One capsule every 6 hours as needed.

      • Children—Use and dose must be determined by your doctor.


    • For oral dosage form (solution):
      • Adults—5 milliliters (mL) or one teaspoonful every 6 hours as needed. However, the dose is usually not more than 60 mL (12 teaspoonfuls) per day.

      • Children—Use and dose must be determined by your doctor.


    • For oral dosage form (tablets):
      • Adults—One tablet every 6 hours as needed. However, the dose is usually not more than 6 to 12 tablets per day.

      • Children—Use and dose must be determined by your doctor.



Missed Dose


If you miss a dose of oxycodone and acetaminophen, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Flush any unused capsules, liquid, or tablets down the toilet.


Precautions While Using oxycodone and acetaminophen


It is very important that your doctor check your progress while you are taking oxycodone and acetaminophen. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it.


It is against the law and dangerous for anyone else to use your medicine. Keep your unused tablets in a safe and secure place. People who are addicted to drugs might want to steal oxycodone and acetaminophen.


oxycodone and acetaminophen will add to the effects of alcohol and other CNS depressants (medicines that can make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for allergies or colds; sedatives, tranquilizers, or sleeping medicine; other prescription pain medicine or narcotics; medicine for seizures or barbiturates; muscle relaxants; or anesthetics, including some dental anesthetics. Also, there may be a greater risk of liver damage if you drink three or more alcoholic beverages while you are taking acetaminophen. Do not drink alcoholic beverages, and check with your doctor before taking any of these medicines while you are using oxycodone and acetaminophen.


oxycodone and acetaminophen may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions.


Dizziness, lightheadedness, or fainting may occur when you get up suddenly from a lying or sitting position. Getting up slowly may help lessen this problem. Also, lying down for a while may relieve the dizziness or lightheadedness.


oxycodone and acetaminophen may make you dizzy, drowsy, or lightheaded. Make sure you know how you react to oxycodone and acetaminophen before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert.


Check with your doctor right away if you have pain or tenderness in the upper stomach; pale stools; dark urine; loss of appetite; nausea; unusual tiredness or weakness; or yellow eyes or skin. These could be symptoms of a serious liver problem.


oxycodone and acetaminophen may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Stop using oxycodone and acetaminophen and call your doctor right away if you have a rash; itching; hoarseness; trouble breathing; trouble swallowing; or any swelling of your hands, face, or mouth while you are using oxycodone and acetaminophen.


Using narcotics for a long time can cause severe constipation. To prevent this, your doctor may direct you to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet. Be sure to follow the directions carefully, because continuing constipation can lead to more serious problems.


If you have been using oxycodone and acetaminophen regularly for several weeks or longer, do not change your dose or suddenly stop using it without checking with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely. This may help prevent worsening of your condition and reduce the possibility of withdrawal symptoms, such as abdominal or stomach cramps, anxiety, fever, irritability, nausea, restlessness, runny nose, sweating, tremors, or trouble with sleeping.


Using oxycodone and acetaminophen while you are pregnant may cause serious unwanted effects in your newborn baby. Tell your doctor right away if you think you are pregnant or if you plan to become pregnant while using oxycodone and acetaminophen.


Before you have any medical tests, tell the medical doctor in charge that you are taking oxycodone and acetaminophen. The results of some tests may be affected by oxycodone and acetaminophen.


Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines, especially those containing acetaminophen (Tylenol (R)), and herbal or vitamin supplements.


oxycodone and acetaminophen Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


More common
  • Abdominal or stomach pain

  • black, tarry stools

  • chills

  • dark urine

  • dizziness

  • fever

  • headache

  • itching

  • light-colored stools

  • loss of appetite

  • nausea

  • rash

  • unpleasant breath odor

  • unusual tiredness or weakness

  • vomiting of blood

  • yellow eyes or skin

Rare
  • Cough or hoarseness

  • fever with or without chills

  • general feeling of tiredness or weakness

  • lower back or side pain

  • painful or difficult urination

  • sore throat

  • sores, ulcers, or white spots on the lips or in the mouth

  • unusual bleeding or bruising

Incidence not known
  • Back, leg, or stomach pains

  • bleeding gums

  • bloating

  • blood in the urine or stools

  • blue lips and fingernails

  • blurred vision

  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

  • chest pain or discomfort

  • clay-colored stools

  • cloudy urine

  • clumsiness

  • confusion

  • constipation

  • coughing that sometimes produces a pink frothy sputum

  • decrease in the frequency of urination

  • decrease in urine volume

  • decreased awareness or responsiveness

  • decreased frequency or amount of urine

  • decreased urination

  • difficult or labored breathing

  • difficult or painful urination

  • difficult, fast, noisy breathing, sometimes with wheezing

  • difficulty in passing urine (dribbling)

  • difficulty with swallowing

  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

  • drowsiness

  • dry mouth

  • extremely shallow or slow breathing

  • fainting

  • fast or deep breathing

  • fast, slow, irregular, pounding, or racing heartbeat or pulse

  • feeling of warmth

  • general body swelling

  • greatly decreased frequency of urination or amount of urine

  • hives or welts

  • increase in heart rate

  • increased blood pressure

  • increased sweating

  • increased thirst

  • indigestion

  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

  • lightheadedness

  • low body temperature

  • muscle aches

  • muscle tremors

  • muscle weakness

  • nervousness

  • noisy breathing

  • nosebleeds

  • numbness or tingling in the hands, feet, or lips

  • pains in the stomach, side, or abdomen, possibly radiating to the back

  • pale skin

  • pinpoint red spots on the skin

  • pounding in the ears

  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

  • rapid, deep breathing

  • rapid, shallow breathing

  • redness of the face, neck, arms, and occasionally, upper chest

  • redness of the skin

  • restlessness

  • seizures

  • severe constipation

  • severe sleepiness

  • severe vomiting

  • shivering

  • shortness of breath

  • skin blisters

  • skin rash

  • sleepiness

  • slow or irregular breathing

  • sore throat

  • stomach cramps

  • stomach pain, continuing

  • sudden decrease in the amount of urine

  • sunken eyes

  • sweating

  • swelling in the legs and ankles

  • swelling of the face, fingers, or lower legs

  • thirst

  • tightness in the chest

  • tiredness

  • troubled breathing

  • unpleasant breath odor

  • upper right abdominal or stomach pain

  • vomiting

  • vomiting of blood

  • weak or feeble pulse

  • weakness or heaviness of the legs

  • weight gain

  • wheezing

  • wrinkled skin

Get emergency help immediately if any of the following symptoms of overdose occur:


Symptoms of overdose
  • Bluish lips or skin

  • change in consciousness

  • cold, clammy skin

  • extreme sleepiness

  • general feeling of discomfort or illness

  • loss of consciousness

  • no blood pressure or pulse

  • not breathing

  • stopping of heart

  • unconsciousness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common
  • Relaxed and calm

Incidence not known
  • Acid or sour stomach

  • agitation

  • anxiety

  • bad or unusual or unpleasant (after) taste

  • belching

  • change in taste

  • cold sweats

  • constricted, pinpoint, or small pupils (black part of the eye)

  • continuing ringing or buzzing or other unexplained noise in the ears

  • cool, pale skin

  • depression

  • diarrhea

  • difficulty with moving

  • disturbed color perception

  • double vision

  • excess air or gas in the stomach or intestines

  • false or unusual sense of well-being

  • flushed, dry skin

  • fruit-like breath odor

  • full feeling

  • general feeling of discomfort or illness

  • halos around lights

  • hearing loss

  • heartburn

  • increased hunger

  • increased thirst

  • increased urination

  • indigestion

  • joint pain

  • lack or loss of strength

  • muscle cramps or spasms

  • muscle pain or stiffness

  • nervousness

  • night blindness

  • nightmares

  • overbright appearance of lights

  • passing gas

  • rash

  • red eye

  • seeing, hearing, or feeling things that are not there

  • seizures

  • severe sleepiness

  • shakiness

  • sleepiness or unusual drowsiness

  • sleeplessness

  • slurred speech

  • stomach discomfort, upset, or pain

  • stomach fullness

  • sweating

  • swollen joints

  • thirst

  • trouble sleeping

  • troubled breathing

  • tunnel vision

  • unable to sleep

  • unexplained weight loss

  • unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: oxycodone and acetaminophen side effects (in more detail)



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More oxycodone and acetaminophen resources


  • Oxycodone and acetaminophen Side Effects (in more detail)
  • Oxycodone and acetaminophen Use in Pregnancy & Breastfeeding
  • Drug Images
  • Oxycodone and acetaminophen Drug Interactions
  • Oxycodone and acetaminophen Support Group
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AK-Dex ophthalmic


Generic Name: dexamethasone (ophthalmic) (DEX a METH a sone off THAL mik)

Brand Names: AK-Dex, Ocu-Dex


What is AK-Dex (dexamethasone (ophthalmic))?

Dexamethasone ophthalmic is in a class of drugs called corticosteroids. It inhibits processes in the body that cause inflammation. Therefore, the swelling and pain of inflammatory conditions is decreased.


Dexamethasone ophthalmic is used to treat eye inflammation caused by infections, injury, surgery, or other conditions.

Dexamethasone ophthalmic may also be used for purposes other than those listed in this medication guide.


What is the most important information I should know about AK-Dex (dexamethasone (ophthalmic))?


Do not stop using this medication suddenly if you have been using it for several weeks or more. Before stopping, you may need to reduce the dose over several days to prevent side effects.

Contact your doctor if your symptoms begin to get worse or if you do not see any improvement in your condition after a few days.


Do not touch the dropper or tube opening to any surface, including your eyes or hands. The dropper or tube opening is sterile. If it becomes contaminated, it could cause an infection in your eye.

Apply light pressure to the inside corner of your eye (near your nose) after each drop to prevent the fluid from draining down your tear ducts.


Who should not use AK-Dex (dexamethasone (ophthalmic))?


Do not use dexamethasone ophthalmic if you have a bacterial, viral, or fungal infection in your eye without also receiving proper anti-infective treatment. Dexamethasone ophthalmic is in the FDA pregnancy category C. This means that it is not known whether dexamethasone ophthalmic will harm an unborn baby. Do not use this medication without first talking to your doctor if you are pregnant. It is also not known whether dexamethasone ophthalmic passes into breast milk. Do not use dexamethasone ophthalmic without first talking to your doctor if you are breast-feeding a baby.

How should I use AK-Dex (dexamethasone (ophthalmic))?


Use dexamethasone ophthalmic eyedrops or ointment exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.


Wash your hands before using your eyedrops or ointment.


To apply the eyedrops:



  • Shake the bottle gently to be sure the medicine is well mixed. Tilt your head back slightly and pull down on your lower eyelid. Position the dropper above your eye. Look up and away from the dropper. Squeeze out the prescribed number of drops and close your eye. Apply gentle pressure to the inside corner of your eye (near your nose) for about 1 minute to prevent the liquid from draining down your tear duct. If you are using drops in both eyes, repeat the process in the other eye.



To apply the ointment:



  • Hold the tube in your hand for a few minutes to warm it up so that the ointment comes out easily. Tilt your head back slightly and pull down gently on your lower eyelid. Apply a thin film of the ointment into your lower eyelid. Close your eye and roll your eyeball around in all directions for 1 to 2 minutes. If you are applying another eye medication, allow at least 10 minutes before your next application.




Do not touch the dropper or tube opening to any surface, including your eyes or hands. The dropper or tube opening is sterile. If it becomes contaminated, it could cause an infection in your eye. Do not use any eyedrop that is discolored or has particles in it. Store dexamethasone ophthalmic at room temperature away from moisture and heat. Keep the bottle or tube properly capped.

What happens if I miss a dose?


Apply the missed dose as soon as you remember. However, if it is almost time for your next regularly scheduled dose, skip the missed dose and apply the next one as directed. Do not use a double dose of this medication.


What happens if I overdose?


An overdose of this medication is unlikely to occur. If you do suspect an overdose, call an emergency room or poison control center near you. If the drops or ointment have been ingested, call an emergency center for advice.


What should I avoid while using AK-Dex (dexamethasone (ophthalmic))?


Do not touch the dropper or tube opening to any surface, including your eyes or hands. The dropper or tube opening is sterile. If it becomes contaminated, it could cause an infection in your eye. Use caution when driving, operating machinery, or performing other hazardous activities. Dexamethasone ophthalmic may cause blurred vision. If you experience blurred vision, avoid these activities.

If you wear contact lenses, ask your doctor if you should wear them during treatment with dexamethasone ophthalmic.


AK-Dex (dexamethasone (ophthalmic)) side effects


Serious side effects are not expected with this medication. Rarely, an increase in the pressure inside of the eye, formation of cataracts, or a perforation of the cornea has been reported. Talk to your doctor about any possible side effects.


More commonly, some burning, stinging, irritation, itching, redness, blurred vision, or sensitivity to light may occur.


This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect AK-Dex (dexamethasone (ophthalmic))?


Do not use other eyedrops or eye medications during treatment with dexamethasone ophthalmic without first talking to your doctor.

Before using this medication, tell your doctor if you are taking an oral steroid medication such as prednisone (Deltasone, Orasone, others), methylprednisolone (Medrol), hydrocortisone (Cortef, Hydrocortone), and others.


Drugs other than those listed here may also interact with dexamethasone ophthalmic. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.



More AK-Dex resources


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Where can I get more information?


  • Your pharmacist has additional information about dexamethasone ophthalmic written for health professionals that you may read.

See also: AK-Dex side effects (in more detail)


Pilocarpine Drops


Pronunciation: pye-loe-KAR-peen
Generic Name: Pilocarpine
Brand Name: Examples include Isopto Carpine and Piloptic


Pilocarpine Drops are used for:

Treating certain types of glaucoma (increased pressure in the eye) alone or in combination with other medicines. It may also be used to reverse the effects of other medicines used during eye surgeries or examinations. It may also be used for other conditions as determined by your doctor.


Pilocarpine Drops are a direct-acting miotic. It works by lowering the fluid pressure inside the eyeball by increasing fluid drainage from the eyeball. It also causes the pupils to constrict or get smaller (miosis).


Do NOT use Pilocarpine Drops if:


  • you are allergic to any ingredient in Pilocarpine Drops

  • you have a certain type of glaucoma (eg, pupillary block glaucoma), eye inflammation, or a severe eye infection

Contact your doctor or health care provider right away if any of these apply to you.



Before using Pilocarpine Drops:


Some medical conditions may interact with Pilocarpine Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a detached retina, an eye infection, or chronic obstructive pulmonary disease

  • if you have had a heart attack

Some MEDICINES MAY INTERACT with Pilocarpine Drops. However, no specific interactions with Pilocarpine Drops are known at this time.


Ask your health care provider if Pilocarpine Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Pilocarpine Drops:


Use Pilocarpine Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Pilocarpine Drops are only for the eye. Do not get it in your nose or mouth.

  • To use Pilocarpine Drops in the eye, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eyelid for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.

  • To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.

  • If you miss a dose of Pilocarpine Drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Pilocarpine Drops.



Important safety information:


  • Pilocarpine Drops may cause blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Pilocarpine Drops with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Pilocarpine Drops may cause harm if it is swallowed. If you may have taken it by mouth, contact your poison control center or emergency room right away.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Pilocarpine Drops while you are pregnant. It is not known if Pilocarpine Drops are found in breast milk. If you are or will be breast-feeding while you use Pilocarpine Drops, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Pilocarpine Drops:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Blurred vision; change in vision; eyelid twitching; headache at the temples or around the eyes; increased tearing; nearsightedness; redness or swelling of the eye; temporary stinging or burning.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); detachment of the retina; fast or abnormal heartbeat; increase in blood pressure; poor vision at night.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.



If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include asthma; blurred vision; diarrhea; fainting; increased saliva; increased sweating; irregular heartbeat; vomiting.


Proper storage of Pilocarpine Drops:

Store Pilocarpine Drops at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Pilocarpine Drops out of the reach of children and away from pets.


General information:


  • If you have any questions about Pilocarpine Drops, please talk with your doctor, pharmacist, or other health care provider.

  • Pilocarpine Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Pilocarpine Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

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Ibuprofen Apotex




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  • Netherlands

International Drug Name Search

Thursday, 22 September 2016

Tramamed




Tramamed may be available in the countries listed below.


Ingredient matches for Tramamed



Tramadol

Tramadol hydrochloride (a derivative of Tramadol) is reported as an ingredient of Tramamed in the following countries:


  • Luxembourg

International Drug Name Search

Lipitor



Pronunciation: a-TOR-va-STAT-in
Generic Name: Atorvastatin
Brand Name: Lipitor


Lipitor is used for:

Lowering high cholesterol and triglycerides in certain patients. It also increases high-density lipoprotein (HDL, "good") cholesterol levels. It is used along with an appropriate diet. It is used in certain patients to reduce the risk of heart attack, stroke, chest pain caused by angina, or blood vessel blockage. It is also used in certain patients to reduce the risk of hospitalization for congestive heart failure, or the need for medical procedures to open blocked heart blood vessels. It may also be used for other conditions as determined by your doctor.


Lipitor is an HMG-CoA reductase inhibitor, also known as a "statin." It works by reducing the production of certain fatty substances in the body, including cholesterol.


Do NOT use Lipitor if:


  • you are allergic to any ingredient in Lipitor

  • you have liver problems or unexplained abnormal liver function tests

  • you are pregnant or breast-feeding

  • you are taking conivaptan, mibefradil, or telaprevir

Contact your doctor or health care provider right away if any of these apply to you.



Before using Lipitor:


Some medical conditions may interact with Lipitor. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are able to become pregnant

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have low blood pressure, kidney problems, diabetes, thyroid problems, muscle problems, or a serious infection

  • if you have metabolism, hormonal, or electrolyte problems

  • if you drink alcohol or have a history of seizures, liver problems, or alcohol abuse

  • if you are scheduled for major surgery, or have recently had major surgery, a serious injury, or a stroke

Some MEDICINES MAY INTERACT with Lipitor. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Amiodarone, azole antifungals (eg, fluconazole, itraconazole), colchicine, conivaptan, cyclosporine, daptomycin, delavirdine, diltiazem, dronedarone, fibrates (eg, clofibrate, gemfibrozil), fusidic acid, HCV protease inhibitors (eg, boceprevir, telaprevir), HIV protease inhibitors (eg, ritonavir), imatinib, macrolides (eg, clarithromycin, erythromycin), mibefradil, nefazodone, niacin, quinine, streptogramins (eg, dalfopristin), telithromycin, verapamil, or voriconazole because they may increase the risk of muscle or kidney problems

  • Bosentan, carbamazepine, efavirenz, rifamycins (eg, rifampin), or St. John's wort because they may decrease Lipitor's effectiveness

  • Cimetidine, digoxin, certain hormonal contraceptives (eg, certain birth control pills), ketoconazole, macrolide immunosuppressants (eg, tacrolimus), or spironolactone because the risk of their side effects may be increased by Lipitor

This may not be a complete list of all interactions that may occur. Ask your health care provider if Lipitor may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Lipitor:


Use Lipitor as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Take Lipitor by mouth with or without food.

  • Swallow Lipitor whole. Do not break, crush, or chew before swallowing.

  • Eating grapefruit or drinking grapefruit juice may increase the amount of Lipitor in your blood, which may increase your risk for serious side effects. The risk may be greater with large amounts of grapefruit or grapefruit juice. Avoid large amounts of grapefruit or grapefruit juice (eg, more than one quart daily). Talk with your doctor or pharmacist if you have questions about including grapefruit or grapefruit juice in your diet while you are taking Lipitor.

  • Continue to take Lipitor even if you feel well. Do not miss any doses.

  • If you miss a dose of Lipitor, take it as soon as possible if you remember within 12 hours of the missed dose. If it is more than 12 hours since the missed dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Lipitor.



Important safety information:


  • Drinking alcohol daily or in large amounts may increase the risk of liver problems with Lipitor. Check with your doctor before drinking alcohol while you are taking Lipitor.

  • Follow the diet and exercise program given to you by your health care provider.

  • Tell your doctor or dentist that you take Lipitor before you receive any medical or dental care, emergency care, or surgery.

  • Women who may become pregnant should use effective birth control while taking Lipitor. Check with your doctor if you have questions about using birth control.

  • Report any unexplained muscle pain, tenderness, or weakness to your doctor right away, especially if you also have a fever or general body discomfort.

  • Lab tests, including blood cholesterol levels, creatine phosphokinase (CPK) levels, and liver function, may be performed while you use Lipitor. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

  • Use Lipitor with caution in the ELDERLY; they may be more sensitive to its effects, especially muscle problems.

  • Lipitor should be used with extreme caution in CHILDREN younger than 10 years old and in those who have not reached puberty; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: Do not use Lipitor if you are pregnant. It may cause harm to the fetus. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if Lipitor is found in breast milk. Do not breast-feed while taking Lipitor.


Possible side effects of Lipitor:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Diarrhea; joint pain; mild sore throat; nausea; runny or stuffy nose; stomach upset.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing or swallowing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue); change in the amount of urine produced; dark urine; muscle pain, tenderness, or weakness (with or without fever or fatigue); painful, difficult, or frequent urination; pale stools; persistent loss of appetite; persistent pain, soreness, redness, or swelling of a tendon or joint; red, swollen, blistered, or peeling skin; severe or persistent nausea, vomiting, or stomach pain; unusual tiredness; yellowing of the eyes or skin.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Lipitor side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.


Proper storage of Lipitor:

Store Lipitor at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Lipitor out of the reach of children and away from pets.


General information:


  • If you have any questions about Lipitor, please talk with your doctor, pharmacist, or other health care provider.

  • Lipitor is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Lipitor. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Lipitor resources


  • Lipitor Side Effects (in more detail)
  • Lipitor Use in Pregnancy & Breastfeeding
  • Drug Images
  • Lipitor Drug Interactions
  • Lipitor Support Group
  • 26 Reviews for Lipitor - Add your own review/rating


  • Lipitor Prescribing Information (FDA)

  • Lipitor Consumer Overview

  • Lipitor Monograph (AHFS DI)

  • Lipitor Advanced Consumer (Micromedex) - Includes Dosage Information

  • Atorvastatin Prescribing Information (FDA)



Compare Lipitor with other medications


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  • Prevention of Cardiovascular Disease

Gliclazide Merck




Gliclazide Merck may be available in the countries listed below.


Ingredient matches for Gliclazide Merck



Gliclazide

Gliclazide is reported as an ingredient of Gliclazide Merck in the following countries:


  • Netherlands

International Drug Name Search